Health Issues in Stafford



 

 Health Issues

The Staffordshire Bull Terrier, generally a healthy breed,can suffer from harmful genetic diseases.  Responsible breeders are attempting to breed out these hereditary diseases.Testing can now be done in New Zealand through Genomic Diagnostics ( formally Gentic Technologies Ltd).

1. L-2-HGA Hydroxyglutaric Aciduria

In the past few years a small number of Staffords have been diagnosed with a metabolic disorder, its clinical name is L2 hydroxyglutaric aciduria or L-2-HGA. This condition manifests itself in varied ways with affected dogs displaying behavioural changes and dementia, anxiety attacks, having full blown seizures, as well as exercise intolerance and ataxia (unsteady gait), tremors and muscular stiffness. Dogs from totally different bloodlines have been found to be sufferers and the number of affected dogs diagnosed has risen. The disorder (and a similar linked disorder D-2 HGA) is found in humans, again very rare, but nevertheless devastating for those families affected by it. The disorder has an autosomal recessive method of inheritance, which means that both parents must be carriers of the affected gene to produce affected offspring.

IT IS THEREFORE ADVISABLE THAT ALL BREEDING STOCK BE SCREENED IN ORDER TO ERADICATE THIS CONDITION IN THE FUTURE.

2. HC – HEREDITARY CATARACTS.

It is known that HC is inherited by and automal recessive path (i.e. both parents must be carriers of the defective gene to produce and affected offspring). HC is a progressive condition and this means that although a puppy is not born with cataracts they will start to develop at a juvenile age. (maybe from 8 months onwards), and will progress until the dog is totally blind. This condition is bilateral which means is affects both eyes equally. Thanks to the tireless research by the Animal Health Trust in the UK there is a now a DNA Test for Hereditary Cataracts. 

3. PHPV – PERSITENT HYPERPLASTIC PRIMARY VITREOUS

The mode of inheritance of PHPV is not so clear, but it is known that it is a congenital condition (present at birth) and that it is not progressive. This means that if a puppy is born with PHPV it can be detected by ophthalmic screening from 6 weeks of age and if it is affected, whatever the condition of the problem at that stage it will not change throughout the dogs life.

Either of the above conditions can be operated on, but it is a serious operation and can be traumatic and very expensive. It is not always covered by insurance due to the hereditary nature.

Even though the genetic test is now available for Hereditary Cataracts it is still important to screen for PHPV.

4. PPSC – POSTERIOR POLAR SUBCAPSULAR CATARACT.

This type of cataracts is found in other breeds, particularly the Labrador and Golden Retriever.
It usually remains as a small, punctuate cataract and doesn’t usually lead to sight problems in these two breeds. It has been placed on schedule 3 of the BVA/KC/ISDS Eye Scheme because a number of Staffords that have been through the Scheme have been found to have this type of cataract. This type of cataract cannot be detected through litter screening. The mode of inheritance is unknown and has a variable age of onset.

BREEDING STOCK SHOULD BE TESTED ANNUALLY TO DETERMINE THAT THE DOG IS CERTIFIED CLEAR AT THE TIME OF MATING.         

                                                                                                                                                        Courtesy Staffordshire Bull Terrier Breed Council,UK            

    

For information about the testing or to obtain swab kits to take to your Vet to do
Contact:
Alana  Good
NZ Sales Representative
Genomic Diagnostics
Phone (09) 434-4345                                                                                                
Mobile: 021 189 5515
Email:
[email protected]



                                                                                                                                                                
 

 

 

 



Contact Details
Grant & Louise Blackwood
Wellington, NZ
Phone : 0064 4478-9313
Email : [email protected]

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